CONFERENCE DAY ONE LIVE
7:50 am Morning Networking Registration & Coffee
8:50 am Chair’s Opening Remarks
Establishing the Framework from Regulatory Bodies for Bacteriophage Therapies to Improve the Likelihood of Approval
9:00 am Launching a National Framework for Compassionate Use of Bacteriophages
Synopsis
- How to advance phage therapies through the clinic in accordance with regulatory guidance
- Diving into different regulatory paths for bacteriophages to become approved therapies
- Navigating the lack of regulations for bacteriophages to develop safe and efficacious therapies
9:30 am Fireside Chat: Dissecting the Guidance from Regulatory Bodies to Develop Bacteriophages Likely to Receive Approval
Synopsis
- How to use current guidance available from regulatory bodies to drive forward bacteriophage clinical trials
- How to derisk the IND filing process in the absence of clear guidance? What are the expectations of data package submission to minimize potential rejection by FDA?
- How will the live biotic category impact bacteriophages, companies and patients?
10:15 am Morning Break & Speed Networking
Synopsis
This networking session is your opportunity to get face-to-face with many of the brightest minds working in the bacteriophage field and establish meaningful business relationships to pursue for the rest of the conference
Unpacking the Manufacturing Challenges in Bacteriophage Production to Deliver High Quality & Stable Therapies to Patients
11:15 am Developing an Off-the-shelf Bacteriophage Cocktail Invention for Cholera in Low- & Middle-Income Countries
Synopsis
- Targeting bacteria that cause cholera with bacteriophage cocktails for high coverage against strains
- Manufacturing encapsulated and spray-dried bacteriophages to remain stable in hot climates with no refrigeration
- Globally distributing and monitoring bacteriophage therapies
New Data!
11:45 am Developing efficient tools for the growing phage ecosystem and its evolving needs
Synopsis
- What information is obtainable from the analysis of phage genomes via bioinformatics
- How to streamline the use of compliant bioinformatic analyses in phage production and research
- How to leverage a phage collection for the good of global phage R&D
12:15 pm Investigating Jumbo Bacteriophages as Personalized & Off-the-shelf Therapies to Difficult-to-Treat Infections
Synopsis
- How to choose an individualized or off-the-shelf phage therapy based on disease indication
- Creating a biobank to develop population-centric bacteriophage therapies
- Exploring inhalation, topical, and intravenous application of bacteriophages to treat a range of infectious diseases
New Company!
New Data!
12:45 pm Networking Lunch
To Engineer or Not to Engineer: Unleashing the True Power of Bacteriophage Therapies with Genetically Modified or Engineered Strains
1:45 pm Data-driven Design of Next-Generation Bacteriophage Therapeutics
Synopsis
- Massively multiplexed bacteriophage characterization unlocks new approaches for proactive engineering of bacteriophages
- Building large, characterized variant pools to predictively resolve bacterial resistance and expand host range
- Genetic engineering of bacteriophages overcomes evolutionary limitations of natural bacteriophages
New Company!
New Data!
2:15 pm Leveraging Engineered Bacteriophages to Target Cancer Cells & Induce an Immune Response Against Tumors
Synopsis
- Utilizing non-lytic filamentous bacteriophages for their shape and ease of purification as the basis for immunotherapy
- Developing the nanofilament TAT003 as an immunotherapy injected directly to the tumor and stick to cancer cells, reshape the surface and activate the immune system
- Fusing cancer protein genes and therapeutic genes to the bacteriophage to achieve antitumor response
New Company!
New Data!
2:45 pm Afternoon Break & Poster Session
Synopsis
Contribute to the conversation and share your cutting-edge research with your fellow bacteriophage community to showcase your breakthrough discoveries to a vast audience of experts. Register your place to submit an abstract for review to showcase your poster*
*Please visit the website for the T&Cs for presenting a poster
Harnessing AI & Machine Learning to Match Bacteriophages to Target Resistant Bacteria for Specific Disease Indications
4:00 pm Optimizing Training Data & AI Models to Match Bacteriophages to Specifically Target Bacterial Strains
Synopsis
- Exploring the role of bioinformatics in preparing bacterial and phage genomes for AI-driven matching
- Selecting the appropriate host-range tests to determine the most effective phages for targeting bacterial strains, enhancing the precision of phage therapy
- Highlighting the development of a global biobank of bacteriophages with an online portal, offering worldwide access to phages
New Company!
New Data!
4:30 pm Utilizing Machine Learning to Find a Matching Bacteriophage to Infectious Strain for Effective Treatment
Synopsis
- Analyzing the bacterial evolution trends and resistance mechanisms to select optimal bacteriophage therapy
- How to model how bacteriophages interact with bacteria to predict the optimal bacteriophage combinations for therapeutics use
- How to develop a strategic bacteriophage therapy approach with AI and machine learning based on real-time data