MONDAY, MARCH 25
Optimizing Phage Discovery & Product Development Through Genomics & Functional Assays
9.00am - 12.00pm
Introduction and Purpose:
Complimenting genomic information with functional assay data illuminates the choices of which phages to develop for therapeutic use. Given this, it is vital to understand which phage candidates to progress from pre-clinical testing to clinical application. This interactive workshop will give you the opportunity to learn about:
- The pipeline of discovery and how this can be facilitated by genomics and sequencing
- Optimizing phage-host matching through functional assays and preclinical models
- Delivering personalized medicine – how to get phage therapy into the hands of physicians and patients
Professor, Yale University
Dr. Paul Turner is the Elihu Professor of Ecology and Evolutionary Biology at Yale University, and Microbiology faculty member at Yale School of Medicine. His research concerns the evolutionary genetics and applied uses of microbes, particularly phages specific to bacterial pathogens. He chaired the American Society for Microbiology (ASM) Division on Evolutionary and Genomic Microbiology and served on the NSF Biological Sciences Advisory Committee, ASM Committee on Minority Education, and multiple National Research Council advisory committees. Dr. Turner was elected American Genetic Association Councilor, Chair of the Gordon Research Conference on Microbial Population Biology, and Chair of the CNRS Jacques Monod Conference on Viral Emergence. He chaired the Watkins Graduate Research Fellowship award committee for ASM, and received the E.E. Just Endowed Research Fellowship and William Townsend Porter Award from Marine Biological Laboratory, and fellowships from Woodrow Wilson Foundation, NSF, NIH and HHMI. He is author of nearly 100 scholarly journal articles, reviews and book chapters on microbiology and the ecology and evolution of infectious diseases. Dr. Turner served as Departmental Chair and Director of Graduate Studies, and most recently as Dean of Science at Yale University.
Associate Research Scientist, Yale University
Ben Chan is an associate research scientist at Yale University. His research focuses on the isolation and characterization of bacteriophages that utilize virulence factors and proteins involved in antibiotic resistance and their subsequent clinical application to treat difficult to manage infections.